Tuesday, August 24, 2010

Comparison and Combination of Spectroscopic Techniques for Detection of Counterfeit Medicines

ScienceDirect.com has made available an online report comparing spectroscopic techniques in the detection of counterfeit medications.

In this highly technical report, scientists studied Fourier transform infrared spectroscopy (FT-IR), near infrared spectroscopy (NIR) and Raman spectroscopy to determine which techniques and associations were the best for discriminating genuine from counterfeit and imitations samples.

The medications tested were counterfeit and imitations of Viagra and Cialis two of the most counterfeited products globally.

According to the report:

It is shown that for the Viagra® samples, the best results were provided by a combination of FT-IR and NIR spectroscopy. On the other hand, the best results for the Cialis® samples were provided by the combination of NIR and Raman spectroscopy (1400–1190 cm−1).

These techniques not only permitted a clear discrimination between genuine and counterfeit or imitation samples but also the distinction of clusters among illegal samples. This might be interesting for forensic investigations by authorities.

Secure Pharma Chain endorses all techniques and testing as it relates to being able to detect and interdict fraudulent, adulterated and counterfeit medication however technologies are in use today within the supply chain that allow for the accurate testing of pharmaceuticals within their sealed, unit of sale container.

Unlike Spectroscopy, these technologies do not require destruction or degradation of the product, laboratory testing or technicians to run and analyze testing results.

EDXRD allows the end user to deploy forensic level testing without opening up the container for testing or sample prep. Additionally EDXRD can accurately test products within the supply chain by warehouse resources within seconds.

To date the EDXRD testing has accurately, efficiently and effectively protected the supply chain end user from receiving or shipping adulterated, fraudulent or counterfeit drugs including Cialis and Viagra.

Spectroscopy is an excellent technology when you need very specific forensic sampling, but when you need to know if your inventories are safe before you ship them,
you don't need a laboratory to interdict counterfeit medications.

To read the entire survey report, visit: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TGX-504127R-1&_user=10&_coverDate=11%2F02%2F2010&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=f9acd7f0661b04a5da0138dbac9966fa.

To learn more about EDXRD anti-counterfeiting technologies, visit: http://www.xstreamsystems.net/.

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